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Modulating effects of cowpea incorporated diets on serum lipids and serum antioxidant activity in Wistar rats

Authors:

OS Perera,

LK
About OS

Laboratory of Nutritional Biochemistry, National Institute of Fundamental Studies, Hantana Road, Kandy.

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R Liyanage ,

LK
About R
Laboratory of Nutritional Biochemistry, National Institute of Fundamental Studies, Hantana Road, Kandy.
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P Weththasinghe,

LK
About P

Department of Animal Science, Faculty of Agriculture, University of Peradeniya, Peradeniya.

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BC Jayawardana,

LK
About BC

Department of Animal Science, Faculty of Agriculture, University of Peradeniya, Peradeniya.

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JK Vidanarachchi,

LK
About JK

Department of Animal Science, Faculty of Agriculture, University of Peradeniya, Peradeniya.

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P Fernando,

LK
About P

Veterinary Research Institute, Gannoruwa, Peradeniya.

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R Sivakanesan

LK
About R

Department of Biochemistry, Faculty of Medicine, University of Peradeniya, Peradeniya.

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Abstract

The effect of incorporation of four Sri Lankan cowpea cultivars in experimental diets on serum lipids and serum antioxidant activity (AOA) in Wistar rats was investigated. Seven-week-old male Wistar rats (five groups, five per group) were fed with 20 % fat as a control diet (CD) in comparison with 20 % fat enriched diets containing 20 % whole cowpea powder from cowpea cultivars [Bombay (BO), Waruni (WA), Dawala (DA) and MI 35 (MI)] for six weeks. A lower serum total cholesterol concentration (TC) (p < 0.05) and a higher (p < 0.05) serum AOA in WA, BO, and MI diet fed rats were observed compared to the CD fed group. Higher serum AOA in WA and BO fed rats was accompanied by the higher AOA and total phenolic content (TPC). A lower (p < 0.05) serum low density lipoprotein concentration (LDL-C) was observed in all cowpea diets fed rats, and lower (p < 0.05) serum triacylglycerol (TG) and higher (p < 0.05) high density lipoprotein (HDL-C) levels were observed in WA and MI fed groups, respectively compared to CD fed groups. Cowpea incorporated experimental diets modulate serum lipids and serum AOA in Wistar rats.

How to Cite: Perera, O., Liyanage, R., Weththasinghe, P., Jayawardana, B., Vidanarachchi, J., Fernando, P. and Sivakanesan, R., 2016. Modulating effects of cowpea incorporated diets on serum lipids and serum antioxidant activity in Wistar rats. Journal of the National Science Foundation of Sri Lanka, 44(1), pp.69–76. DOI: http://doi.org/10.4038/jnsfsr.v44i1.7983
Published on 31 Mar 2016.
Peer Reviewed

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