Short Communications
In vitro thrombolytic activity of Sri Lankan black tea, Camellia sinensis (L.) O.Kuntze
Authors:
WD Ratnasooriya ,
Department of Zoology, Faculty of Science, University of Colombo, Colombo 03, LK
TSP Fernando,
Department of Zoology, Faculty of Science, University of Colombo, Colombo 03, LK
PP Madubashini
Department of Zoology, Faculty of Science, University of Colombo, Colombo 03, LK
Abstract
This study examined the thrombolytic potential of black tea [Camellia sinensis (L) O. Kuntze.] in vitro, using Sri Lankan high grown Dust grade No: 1 black tea and goat blood. Different concentrations of tea were made in isotonic saline (2.5, 5, 10 and 20 mg/mL) and added to preclotted blood and the clot lysis activity was determined (in terms of weight and expressed as % of lysis) following 90 minute incubation at 37°C. The results showed that tea induced mild to moderate (121-520%) and significant (p < 0.05) clot lysis activity. This effect was dose-related. However, the clot lytic activity of black tea was markedly lower than streptokinase (0.1 mg/mL). It is concluded that Sri Lankan black tea possesses fast acting mild to moderate thrombolytic activity in vitro when tested on goat blood.
Key words: Black tea, Camellia sinensis (L.) O. Kuntze, clot lysis, Dust grade tea, thrombolytic
doi:10.4038/jnsfsr.v36i2.151
Journal of the National Science Foundation of Sri Lanka 36 (2) 179-181
How to Cite:
Ratnasooriya, W., Fernando, T. and Madubashini, P., 2008. In vitro thrombolytic activity of Sri Lankan black tea, Camellia sinensis (L.) O.Kuntze. Journal of the National Science Foundation of Sri Lanka, 36(2), pp.179–181. DOI: http://doi.org/10.4038/jnsfsr.v36i2.151
Published on
25 Jun 2008.
Peer Reviewed
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